Alice, having escaped from the Umbrella facility, finds Raccoon City overrun with the undead. Along with a group of survivors that includes Jill Valentine, she must find the daughter of Dr. Charles Ashford, who will then provide them with a way out of the city before it is nuked by Umbrella in a cover-up attempt. Meanwhile, they are being hunted by the Nemesis, another one of Umbrella’s experiments.